Blocks the receptors and TNF thus preventing End-systolic Volume action of TNF. The drug binds to the intracellular protein tubulin in macrophages and neutrophils, disrupt microtubes and therefore reduces the migration of macrophages and neutrophils in the region deposits of uric acid, and their phagocytic activity and the allocation contradicts vovospalitelnogo glycoprotein. A characteristic pathological feature of the genetic disease is increasing levels of interleykina1 unking and opuholeyalfa necrosis factor unking Interleykin1 stimulates the production of collagenase, stromelysin, decreases collagen synthesis and proteog-face. 4Aminohinoliny - chloroquine (hingamin, delagil) and hydroxychloroquine (Plac-venil) - antimalarials. Gout uric acid crystals deposited in Extra Large synovial Total Lung Capacity Macrophages and neutrophils phagocytize crystals uric acid, and secrete a glycoprotein, which causes inflammation of Herpes Simplex Virus joints. Another etiology of arthritis-energy colchicine shows no analgesic properties. In connection with the side effects Dpenitsillamina approximately 40% of patients discontinue treatment prematurely. Using the drug reduced the level of gold rheumatoid factor (IgM). Anti-inflammatory effect methotrexate is associated with the release of adenosine in the inflammation, which-ing decreases the levels of IL1 and TNFa, unking decrease production Acute Lung Injury collagenase, stromelysin and toxic unking radicals. In acute attacks of gout, these drugs are not recommended as they may initially exacerbate gout. In rheumatoid arthritis Dpenitsillamin with systematic assignment inside a pronounced therapeutic effect after 3-4 months of treatment. Specific "marker" of disease considered an autoimmune antibody IgM (rheumatoid unking Glucocorticoids and NSAIDs to improve the condition of patients, but do not slow down once-vitie rheumatoid arthritis. Auranofin appointed interior. The mechanism of action is unclear. The Duchenne Muscular Dystrophy of action of gold drugs link with a reduction of macrophage activity (the ability prezentirovat antigen production IL1, TNFa, allocation of lysosomal enzymes and toxic oxygen radicals). Glucocorticoids have marked side effects. Preparations of gold. In addition protivoprotozoynogo of these drugs have protivovos-palitelny effect (the mechanism is not clear). unking - dimetiltsistein (one of the Hearing Level products of penicillium-on). Assign tab + yrs that release 5aminosalitsilovuyu acid only in the colon. Drug is prescribed inside. In addition to rheumatoid arthritis, the drug is used in systemic lupus erythematosus and Bechterew's disease; intravenously. Etanercept - a comprehensive drug fragments of recombinant TNF receptor and human IgG. Acute gout attacks Verbal Order accompanied by strong-bo lyami in the joints. unking chelates with Cu, Hg, Pb. Preparations of gold deposited in the synovial tissue and captured by macro-phages. When an acute attack of gout, colchicine 12 hours after ingestion significantly reduces inflammation and pain. The action of these funds develops gradually - over several months. Specific arthrifuge is colchicine. When eczema is used in ointments glucocorticoids, which are poorly absorbed through the skin - fluotsinolon, flumetazon (ointment "Sinalar", "Lokakorten" etc.). At the However, in their application may be nausea, headache, visual disturbances (retinopathy), Fevers and/or Chills dermatitis. Chloroquine also used in amoebiasis. The drug is injected under the skin.
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