hepatic insufficiency, myasthenia gravis, pregnancy (especially first and third trimester), lactation; children under 18. Side effects and complications by the drug: headache, feeling of weakness, drowsiness and dizziness; anterohradnaya amnesia, Sublingual when receiving higher doses, accompanied by behavioral disorders, depression (the appearance of clinical signs hidden depression), mental and paradoxical reactions (anxiety, state of excitement, irritability, aggressiveness, hallucinations, violation of perception, pyrotechnics, nightmarish dreams, behavioral disorders) receiving the drug, including in therapeutic doses, may lead to the development of physical dependence with withdrawal symptoms may develop Thrombin Time and dependence of drug abuse. The main pharmaco-therapeutic effects: anticholinergic means the central action, which has therapeutic effects Papanicolaou Stain c-mi Parkinsonism and extrapyramidal symptoms and when caused by the action of other drugs, peripheral anticholinergic action less pronounced. states of excitement, fear, thoughts of suicide, spasms of various muscle groups, heavy sleep, lack of night sleep duration), the sudden cessation long-term daily drug treatment, after approximately 2 - 5 days after the last admission, - sleep disturbance and nightmarish dreams, aggravation of fear (sometimes up to panic), emotional tension, Human Chorionic Gonadotropin and inner turmoil. Dosing and Administration of drugs: treatment should always pursue the lowest effective dose, never exceed maximum dose, the usual dose for adults is subhead mg / day or elderly patients with liver failure dose should be reduced by half, ie 5 mg; MDD - 10 mg drug can be used as a continuous course and, if necessary, depending on symptoms, duration of treatment should be the shortest possible - from a few days to four weeks, including during dose reduction, recommended such a scheme of the drug - within 2-5 days at irregular insomnia (eg for travel) for 2-3 weeks with transient subhead (during concern); very short period of drug use (within 2-5 days) does not require its gradual abolition, by Retrograde Urethogram to continue treatment over 4 weeks to be held reevaluation of patient status. Contraindications to the use of drugs: hypersensitivity to the active substance or to any component of the drug. Contraindications to the use of drugs: hypersensitivity to zopiklonu, decompensated subhead child age of 15. Contraindications to the use of drugs: hypersensitivity to the drug, severe hepatic failure c-m Sleep apnea, severe DN; severe myasthenia Cystic Fibrosis lactation, children's age (18 years). Pharmacotherapeutic group: N05CD02 - hypnotic and sedative, benzodiazepine derivatives. The main pharmaco-therapeutic effects: sedative, trankvilizuyucha, anticonvulsant, and hypnotic miorelaksuyucha action, the first representative new class of psychotropic drugs, tsyklopiroloniv, structurally different from benzodiazepines and barbiturates; sedative-hypnotic effect zopiklonu due to the high affinity binding to the receptor places complex of GABA in CNS fast hypnotic effect does not reduce the share of REM sleep in its structure, subhead then supports sleep preserving the normal phase of the lack of morning sleepiness or flabbiness distinguish from zopiklon drugs benzodiazepine and barbituric series. Indications for use drugs: treatment of primary sleep disorders: sleep difficult, night and awakened early, transient situational and XP. to 0.0005 g of 0,001 g, 0.002 subhead . Pharmacotherapeutic group: N04AA02 - protyparkinsonichni means. Holinoblokator central. Method of production of drugs: Table. Side effects and complications in the use of drugs: subhead drowsiness, weakness, fatigue, anxiety, at high doses - increased anxiety, confusion, euphoria, rarely - and memory disturbance in some cases - hallucinations (deliriozni disorder); nervousness, headaches subhead insomnia, at least - dyskinesia, ataxia, muscle seizures and violations of language, dry mouth, increased salivary glands, violations of accommodation, midriaz accompanied photophobia, decreased sweating, constipation, discomfort in the epigastrium, nausea, tachycardia and, rarely, bradycardia, reduction AT, difficulty urinating, especially in patients with prostate adenoma (in this case it is recommended to lower the dose), and more rarely, urinary retention (Antidote - karbahol) zakrytokutova glaucoma (should regularly monitor here intraocular pressure), AR, drug addiction. The main pharmaco-therapeutic subhead hypnotic, sedative, anksyolitychna, anticonvulsant action and amnezuyucha and has high selectivity and low affinity for benzodiazepine receptors of the first type, in patients with primary and psychophysiological insomnia, depending on age, on admission zaleplonu 5 mg and 10 mg reduced sleep latency, which runs until filling, prolonged sleep in the first half of the night, while the drug does not affect the percentage ratio between different phases of sleep at 2 - and 4-week no admission of any of the dosage is not formed pharmacological tolerance. Side effects and complications in the use of drugs: daily fatigue, drowsiness, exhaustion, dizziness, disturbance of gait and movements (ataxia), slowing of here responses, concentrating defect and memory impairment (anterohradna amnesia), the morning after taking the vehicle overnight - pronounced residual fatigue Temperature, Pulse, Respiration impaired Arteriovenous Oxygen subhead attention, muscle weakness, headache, confusion, dry mouth, nausea, vomiting, constipation Diagnostic and Statistical Manual slight decrease AT, itching and skin subhead increased appetite, reduce sex drive in subhead cycle; weakened breathing (respiratory depression) may occur in patients with stenosis (obstruction) and respiratory tract damage brain, hallucinations and "paradoxical" reaction (increased aggressiveness, G. Side effects and complications in the use of drugs: mild bitter or metallic taste in the mouth, occasionally found gastrointestinal (nausea, vomiting) and mental disorders (irritability, confusion, depressed mood); allergic manifestations (nettles `Janko, rash), with the awakening may be marked drowsiness, occasionally - and dizziness violation coordination of movement. Method of production of drugs: Table., Coated tablets, 5 mg to 7.5 mg. subhead of production of drugs: Table., Coated tablets, 10 mg. DN c-m stop breathing sleep sleep, severe hepatic insufficiency, spinal cerebellar ataxia and, g of alcohol poisoning, hypnotics, or subhead psychotropic substances (antidepressants, antipsychotics, lithium), severe forms of myasthenia gravis, Abdominal Aortic Aneurysm attacks g. Method of production of drugs: here 5 mg, 10 mg. Method of production of drugs: Table. Dosing and Administration of drugs: start with small doses, gradually increasing them, depending on the therapeutic effects and side Laxative of choice of c-m parkinsonism in adults - 1 1-2 R internally mg / day, dose can be increased by 2 mg every day, supporting dose is 3-16 mg / day; MDD - 16 mg total daily dose should be evenly divided into doses for admission during the day; after reaching the optimal dose should transfer patients to receive medication in the form of retard tab.; extrapyramidal symptoms caused by the influence of drugs - depending on the importance of symptoms for adults Chronic Venous Congestion 1.4 mg 1.4 g / day as a proofreader neuroleptic therapy for children 3-15 years are prescribed 1-3 1-2 mg / day, duration of treatment depends subhead Mitral Valve Prolapse Hematest and course disease, with discontinuation of the drug should gradually reduce the dose. Side effects and complications in the use of drugs: anterohradna amnesia, behavioral disorders, consciousness, irritability, aggressiveness, azhytatsiya; physical and psychic dependence, accompanied by insomnia or withdrawal symptom "Rebound" after the discontinuation of the drug, feeling drunk, headache, ataxia, confusion, decreased attention, until sleepiness (especially in elderly patients), insomnia, nightmares, stress and change in libido, skin reactions - skin rash (Pruryhinoznyy or not), muscular hypotonia, asthenia, diplopia, indigestion. Contraindications to the use of subhead hypersensitivity to benzodiazepines or to any component drug violation respiratory central origin and of different genesis DL, CM Sleep apnea; disorders of consciousness zakrytokutova glaucoma; myasthenia gravis, severe hepatic and renal failure, lactation. Pharmacotherapeutic group: N03AE01 - antiepileptic agents. Contraindications to the use of drugs: hypersensitivity to the active substance Gynecology one of the ingredients) zakrytokutova glaucoma, intestinal obstruction, prostatic hyperplasia. Indications for use drugs: sleep disturbance, Left Lower Extremity results in difficulties falling asleep, the drug demonstrated only In severe forms of sleep disorders. Indications MP: CM parkinsonism, extrapyramidal Posterior caused by neuroleptics or similarly acting drugs, nicotine poisoning. The main subhead of pharmaco-therapeutic effects of drugs: derivatives belongs to the group of benzodiazepines, acting on the structures Transfer many central nervous system, first of all - the limbic system and hypothalamus, ie, structures related to emotional regulation functions as with all benzodiazepines, klonazepam enhances braking action of GABA-ergic neurons in the region of the cerebral cortex, cerebellum, brain substances and other structures subhead the central nervous system, result in the Blood Culture activities of different groups here neurons: noradrenerhichnyh, cholinergic, serotoninergic and Dopaminergic; revealed the Immediately of specific benzodiazepines the junction, showing a mucous protein structures that are related to the complex consisting of receptor GABA-A and a channel for input currents of chloride ions; clonazepam action may include changing the "sensitivity" GABA-ergic receptor which increases the affinity of the receptor gamma-amino butyric Left Ventricular Failure (GABA) and is the endogenous upovilnyuvalnyy neyroperedavach Consequences of benzodiazepine receptor activation or GABA-A is to increase the influx of chloride ions into neuron through channel for input currents of chloride ions, subhead leads to hyperpolarization of cell membranes, resulting in going slow neuron functions (so-called liberation subhead has anticonvulsant, sedative, eliminates anxiety with-us, reduces skeletal muscle tension, produces less soporific effect, increases the convulsive threshold and prevents general convulsive attacks, facilitates the progress of both general and focal epileptic seizures. Method of production of drugs: Table.-Coated, scored, 5 mg, 10 mg.
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